Cell culture aging: Insights for cell aging in vivo?
نویسندگان
چکیده
منابع مشابه
Recent Advances in T Cell Signaling in Aging
The immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. Well characterized are age related defect in T cell functions and cell mediated immunity. Although it is well established that the functional properties of T cells decrease with age, its biochemical and molecular nature is...
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the immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. well characterized are age related defect in t cell functions and cell mediated immunity. although it is well established that the functional properties of t cells decrease with age, its biochemical and molecular nature is p...
متن کاملT cell aging
The immune system exhibits profound age-related changes, collectively termed immunosenescence. The most visible of these is the decline in protective immunity, which results from a complex interaction of primary immune defects and compensatory homeostatic mechanisms. The sum of these changes is a dysregulation of many processes that normally ensure optimal immune function. Recent advances sugge...
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ژورنال
عنوان ژورنال: Aging Clinical and Experimental Research
سال: 1999
ISSN: 1720-8319
DOI: 10.1007/bf03399629